Role of Pancreatic Stellate Cells in Chemoresistance in Pancreatic Cancer
Pancreatic cancer is highly chemoresistant. A major contributing factor is the characteristic extensive stromal or fibrotic reaction, which comprises up to 90% of the tumour volume. Over the last decade there has been intensive research into the role of the pro-fibrogenic pancreatic stellate cells (...
Auteurs principaux: | , , , , , , , |
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Format: | Article |
Langue: | English |
Publié: |
Frontiers Media S.A.
2014-04-01
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Collection: | Frontiers in Physiology |
Sujets: | |
Accès en ligne: | http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00141/full |