Monoglyceride Lipase Deficiency Is Associated with Altered Thrombogenesis in Mice

Monoglyceride Lipase Deficiency Is Associated with Altered Thrombogenesis in Mice

Monoglyceride lipase (MGL) hydrolyzes monoacylglycerols (MG) to glycerol and one fatty acid. Among the various MG species, MGL also degrades 2-arachidonoylglycerol, the most abundant endocannabinoid and potent activator of the cannabinoid receptors 1 and 2. We investigated the consequences of MGL de...

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Bibliographic Details
Main Authors: Madeleine Goeritzer, Katharina B. Kuentzel, Sarah Beck, Melanie Korbelius, Silvia Rainer, Ivan Bradić, Dagmar Kolb, Marion Mussbacher, Waltraud C. Schrottmaier, Alice Assinger, Axel Schlagenhauf, René Rost, Benjamin Gottschalk, Thomas O. Eichmann, Thomas Züllig, Wolfgang F. Graier, Nemanja Vujić, Dagmar Kratky
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
platelets
MGL
in vitro and in vivo thrombus formation
platelet activation
platelet aggregation
Online Access:https://www.mdpi.com/1422-0067/24/4/3116

Internet

https://www.mdpi.com/1422-0067/24/4/3116

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