Major Virion Tegument Protein VP22 Targets Nuclear Matrix and Chromatin upon Entry into Cells during Productive Herpes Simplex Virus 1 Infection

HSV-1 major tegument protein VP22 is present in multiple subcellular locations in the late stages of productive viral infection. We initially performed a detailed time course experiment and observed that VP22 was detected in nuclear and nuclear matrix fractions as early as 4 hpi. The goal was to det...

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Bibliographic Details
Main Authors: Isabella Chi, John A. Blaho
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/12/3/521