Pancreatic ductal adenocarcinoma holds unique features to form an immunosuppressive microenvironment: a narrative review

Pancreatic ductal adenocarcinoma (PDAC) is the most common type and composes about 90% of pancreatic cancer featured with high intra-tumoral heterogeneity and poor prognosis, which has been considered the least immunogenic cancer for decades. However, this characterization might be over-simplistic,...

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Bibliographic Details
Main Authors: Qiang Zhou, Dan Chen, Junfeng Zhang, Jifeng Xiang, Tao Zhang, Huaizhi Wang, Yanyan Zhang
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2022-12-01
Series:Journal of Pancreatology
Online Access:http://journals.lww.com/10.1097/JP9.0000000000000109