Plastin 3 down-regulation augments the sensitivity of MDA-MB-231 cells to paclitaxel via the p38 MAPK signalling pathway

Plastin 3 down-regulation augments the sensitivity of MDA-MB-231 cells to paclitaxel via the p38 MAPK signalling pathway

Plastin 3 (PLS3) overexpression may serve as a marker for predicting chemotherapeutic outcomes in drug-resistant cancer cells, but the mechanism is unclear. Herein, we show that the down-regulation of PLS3 by PLS3 gene silencing augments the sensitivity of MDA-MB-231 triple-negative breast cancer ce...

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Bibliographic Details
Main Authors: Yan Ma, Wenjia Lai, Minzhi Zhao, Chunyan Yue, Fanghao Shi, Ren Li, Zhiyuan Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Plastin 3
p38 MAPK
sensitivity
paclitaxel
Abraxane
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2019.1576707

Internet

https://www.tandfonline.com/doi/10.1080/21691401.2019.1576707

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