NLRX1 Facilitates Histoplasma capsulatum-Induced LC3-Associated Phagocytosis for Cytokine Production in Macrophages

NLRX1 Facilitates Histoplasma capsulatum-Induced LC3-Associated Phagocytosis for Cytokine Production in Macrophages

LC3-associated phagocytosis (LAP) is an emerging non-canonical autophagy process that bridges signaling from pattern-recognition receptors (PRRs) to autophagic machinery. LAP formation results in incorporation of lipidated LC3 into phagosomal membrane (termed LAPosome). Increasing evidence reveals t...

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Bibliographic Details
Main Authors: Juin-Hua Huang, Chu-Yu Liu, Sheng-Yang Wu, Wen-Yu Chen, Tzu-Hsuan Chang, Hung-Wei Kan, Sung-Tsang Hsieh, Jenny P.-Y. Ting, Betty A. Wu-Hsieh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
LC3-associated phagocytosis
Histoplasma capsulatum
NLRX1
macrophage
non-canonical autophagy
cytokine response
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02761/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02761/full

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