Comprehensive evaluation of plasma microbial cell-free DNA sequencing for predicting bloodstream and local infections in clinical practice: a multicenter retrospective study

Comprehensive evaluation of plasma microbial cell-free DNA sequencing for predicting bloodstream and local infections in clinical practice: a multicenter retrospective study

BackgroundMetagenomic next-generation sequencing (mNGS) of plasma cell-free DNA (cfDNA) shows promising application for complicated infections that cannot be resolved by conventional microbiological tests (CMTs). The criteria for cfDNA sequencing are currently in need of agreement and standardizatio...

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Bibliographic Details
Main Authors: Feng Pang, Wenbin Xu, Hui Zhao, Shuai Chen, Yaxian Tian, Juanjuan Fu, Zhiqing You, Pingping Song, Qingjie Xian, Qigang Zhao, Chengtan Wang, Xiuqin Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
metagenomic next-generation sequencing (mNGS)
plasma cell-free DNA (cfDNA)
bloodstream infections
local infections
ROC curves
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1256099/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2023.1256099/full

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