Immunochemical Methods for Ochratoxin A Detection: A Review
The safety of food and feed depends to a great deal on quality control. Numerous compounds and organisms may contaminate food and feed commodities and thus pose a health risk for consumers. The compound of interest in this review is ochratoxin A (OTA), a secondary metabolite of the fungi Aspergillus...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-04-01
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| Series: | Toxins |
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| Online Access: | http://www.mdpi.com/2072-6651/4/4/244/ |
| _version_ | 1798006044381675520 |
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| author | Eline P. Meulenberg |
| author_facet | Eline P. Meulenberg |
| author_sort | Eline P. Meulenberg |
| collection | DOAJ |
| description | The safety of food and feed depends to a great deal on quality control. Numerous compounds and organisms may contaminate food and feed commodities and thus pose a health risk for consumers. The compound of interest in this review is ochratoxin A (OTA), a secondary metabolite of the fungi Aspergillus and Penicillium. Due to its adverse health effects, detection and quantification are of utmost importance. Quality control of food and feed requires extraction and analysis, including TLC, HPLC, MS, and immunochemical methods. Each of these methods has its advantages and disadvantages. However, with regard to costs and rapidity, immunochemical methods have gained much interest in the last decade. In this review an introduction to immunochemistry and assay design will be given to elucidate the principles. Further, the application of the various formats to the detection and quantification of ochratoxin will be described, including the use of commercially available kits. |
| first_indexed | 2024-04-11T12:48:44Z |
| format | Article |
| id | doaj.art-8f98095d809e4030bb6ba6abc28d7a48 |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-11T12:48:44Z |
| publishDate | 2012-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-8f98095d809e4030bb6ba6abc28d7a482022-12-22T04:23:16ZengMDPI AGToxins2072-66512012-04-014424426610.3390/toxins4040244Immunochemical Methods for Ochratoxin A Detection: A ReviewEline P. MeulenbergThe safety of food and feed depends to a great deal on quality control. Numerous compounds and organisms may contaminate food and feed commodities and thus pose a health risk for consumers. The compound of interest in this review is ochratoxin A (OTA), a secondary metabolite of the fungi Aspergillus and Penicillium. Due to its adverse health effects, detection and quantification are of utmost importance. Quality control of food and feed requires extraction and analysis, including TLC, HPLC, MS, and immunochemical methods. Each of these methods has its advantages and disadvantages. However, with regard to costs and rapidity, immunochemical methods have gained much interest in the last decade. In this review an introduction to immunochemistry and assay design will be given to elucidate the principles. Further, the application of the various formats to the detection and quantification of ochratoxin will be described, including the use of commercially available kits.http://www.mdpi.com/2072-6651/4/4/244/ochratoxin A (OTA)detectionquantificationimmunochemical methods |
| spellingShingle | Eline P. Meulenberg Immunochemical Methods for Ochratoxin A Detection: A Review Toxins ochratoxin A (OTA) detection quantification immunochemical methods |
| title | Immunochemical Methods for Ochratoxin A Detection: A Review |
| title_full | Immunochemical Methods for Ochratoxin A Detection: A Review |
| title_fullStr | Immunochemical Methods for Ochratoxin A Detection: A Review |
| title_full_unstemmed | Immunochemical Methods for Ochratoxin A Detection: A Review |
| title_short | Immunochemical Methods for Ochratoxin A Detection: A Review |
| title_sort | immunochemical methods for ochratoxin a detection a review |
| topic | ochratoxin A (OTA) detection quantification immunochemical methods |
| url | http://www.mdpi.com/2072-6651/4/4/244/ |
| work_keys_str_mv | AT elinepmeulenberg immunochemicalmethodsforochratoxinadetectionareview |