Early molecular diagnosis of BRAF status drives the neurosurgical management in BRAF V600E-mutant pediatric low-grade gliomas: a case report

Early molecular diagnosis of BRAF status drives the neurosurgical management in BRAF V600E-mutant pediatric low-grade gliomas: a case report

Abstract Background To date, this is the only report showing with close and consecutive magnetic resonance images the extremely rapid response of two types of pediatric low-grade gliomas (PLGG) to vemurafenib and its impact on the surgical approach. Cases presentation We report two cases of symptoma...

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Bibliographic Details
Main Authors: Gianluca Piccolo, Antonio Verrico, Giovanni Morana, Gianluca Piatelli, Patrizia De Marco, Valentina Iurilli, Manila Antonelli, Gabriele Gaggero, Antonia Ramaglia, Marco Crocco, Samuele Caruggi, Claudia Milanaccio, Maria Luisa Garrè, Marco Pavanello
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Pediatrics
Subjects:
Case report
Vemurafenib
Neurosurgery
Brain tumors
BRAF
Online Access:https://doi.org/10.1186/s12887-022-03711-6

Internet

https://doi.org/10.1186/s12887-022-03711-6

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