At-line porosity sensing for non-destructive disintegration testing in immediate release tablets

At-line porosity sensing for non-destructive disintegration testing in immediate release tablets

Fully automated at-line terahertz time-domain spectroscopy in transmission mode is used to measure tablet porosity for thousands of immediate release tablets. The measurements are rapid and non-destructive. Both laboratory prepared tablets and commercial samples are studied. Multiple measurements on...

Full description

Bibliographic Details
Main Authors: Prince Bawuah, Mike Evans, Ard Lura, Daniel J. Farrell, Patrick J. Barrie, Peter Kleinebudde, Daniel Markl, J. Axel Zeitler
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Terahertz spectroscopy
Pharmaceutical tablet
Porosity
Disintegration
Real-time release testing
Process analytical technology
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156723000300

Internet

http://www.sciencedirect.com/science/article/pii/S2590156723000300

Similar Items