Learning "graph-mer" motifs that predict gene expression trajectories in development.

A key problem in understanding transcriptional regulatory networks is deciphering what cis regulatory logic is encoded in gene promoter sequences and how this sequence information maps to expression. A typical computational approach to this problem involves clustering genes by their expression profi...

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Bibliographic Details
Main Authors: Xuejing Li, Casandra Panea, Chris H Wiggins, Valerie Reinke, Christina Leslie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2861633?pdf=render