Type 3 deiodinase and consumptive hypothyroidism: a common mechanism for a rare disease

The major product secreted by the thyroid is thyroxine (T4), whereas most of the biologically active triiodothyronine (T3) derives from the peripheral conversion of T4 into T3. The deiodinase enzymes are involved in activation and inactivation of thyroid hormones. Type 1 and type 2 deiodinase (D1 an...

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Bibliographic Details
Main Authors: Cristina eLuongo, Luigi eTrivisano, Fausta eAlfano, Domenico eSalvatore
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00115/full