Detection of Immune Escape and Basal Core Promoter/Precore Gene Mutations in Hepatitis B Virus Isolated from Asymptomatic Hospital Attendees in Two Southwestern States in Nigeria

Detection of Immune Escape and Basal Core Promoter/Precore Gene Mutations in Hepatitis B Virus Isolated from Asymptomatic Hospital Attendees in Two Southwestern States in Nigeria

Several mutations in the surface (S), basal core promoter (BCP), and precore (PC) genes of the hepatitis B virus have been linked to inaccurate diagnosis and the development of immune escape mutants (IEMs) of the infection, which can lead to chronic infection. Understanding the prevalence and spread...

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Bibliographic Details
Main Authors: Oguntope Adeorike Sobajo, Judith Uche Oguzie, Benjamin Adegboyega, Philomena Eromon, Christian Happi, Isaac Komolafe, Onikepe Folarin
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Viruses
Subjects:
HBV genotype E
immune escape mutations
major hydrophilic region
basal core promoter/precore region
southwest
Nigeria
Online Access:https://www.mdpi.com/1999-4915/15/11/2188

Internet

https://www.mdpi.com/1999-4915/15/11/2188

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