Toxoplasma WH3 Δrop18 acts as a live attenuated vaccine against acute and chronic toxoplasmosis

Abstract Toxoplasma gondii is a significant zoonotic pathogen of toxoplasmosis in humans and animals. Here a live attenuated Toxoplasma vaccine of WH3 Δrop18 was developed. The results showed that all mice vaccinated with WH3 Δrop18 were able to survive when challenge with various strains of Toxopla...

Full description

Bibliographic Details
Main Authors: Cong Wang, Shengnan Fu, Xin Yu, Hang Zhou, Famin Zhang, Lingling Song, Ji Zhao, Yun Yang, Jianbing Du, Qingli Luo, Jilong Shen, Li Yu
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00996-9