Across Dimensions: Developing 2D and 3D Human iPSC-Based Models of Fragile X Syndrome

Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and autism spectrum disorder. FXS is caused by a cytosine-guanine-guanine (CGG) trinucleotide repeat expansion in the untranslated region of the <i>FMR1</i> gene leading to the functional loss of the g...

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Bibliographic Details
Main Authors: Azalea Lee, Jie Xu, Zhexing Wen, Peng Jin
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/11/1725