Molecular characterization and temporal expression profiling of presenilins in the developing porcine brain

<p>Abstract</p> <p>Background</p> <p>The transmembrane presenilin (PSEN) proteins, PSEN1 and PSEN2, have been proposed to be the catalytic components of the γ-secretase protein complex, which is an intramembranous multimeric protease involved in development, cell regula...

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Bibliographic Details
Main Authors: Fredholm Merete, Holm Ida E, Bendixen Christian, Larsen Knud, Thomsen Bo, Madsen Lone B, Jørgensen Arne L, Nielsen Anders L
Format: Article
Language:English
Published: BMC 2007-09-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/8/72