Early Oral Administration of Ginseng Stem-Leaf Saponins Enhances the Peyer’s Patch-Dependent Maternal IgA Antibody Response to a PEDV Inactivated Vaccine in Mice, with Gut Microbiota Involvement

Early Oral Administration of Ginseng Stem-Leaf Saponins Enhances the Peyer’s Patch-Dependent Maternal IgA Antibody Response to a PEDV Inactivated Vaccine in Mice, with Gut Microbiota Involvement

Neonatal piglets during the first week of life are highly susceptible to porcine epidemic diarrhoea virus (PEDV) infection, with mortality rates reaching 80–100%. Passive lactogenic immunity remains the most effective way to protect neonates from infection. Although safe, inactivated vaccines provid...

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Bibliographic Details
Main Authors: Fei Su, Junxing Li, Yin Xue, Bin Yu, Shiyi Ye, Lihua Xu, Yuan Fu, Xiufang Yuan
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Vaccines
Subjects:
GSLS
PEDV
mucosal immune enhancement
maternal IgA
Peyer’s patches
gut microbiota
Online Access:https://www.mdpi.com/2076-393X/11/4/830

Internet

https://www.mdpi.com/2076-393X/11/4/830

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