PTH 1-34 promoted bone formation by regulating iron metabolism in unloading-induced bone loss

PTH 1-34 (teriparatide) is approved by FDA for the treatment of postmenopausal osteoporosis. Iron overload is a major contributing factor for bone loss induced by unloading. Whether iron metabolism is involved in the regulation of PTH 1-34 on unloading-induced osteoporosis has not yet been reported....

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Bibliographic Details
Main Authors: Jingmin Che, Weihao Ren, Xin Chen, Fang Wang, Gejing Zhang, Peng Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1048818/full