The decoy oligodeoxynucleotide against HIF-1α and STAT5 ameliorates atopic dermatitis-like mouse model

The decoy oligodeoxynucleotide against HIF-1α and STAT5 ameliorates atopic dermatitis-like mouse model

Atopic dermatitis (AD) is a common inflammatory skin disease caused by an immune disorder. Mast cells are known to be activated and granulated to maintain an allergic reaction, including rhinitis, asthma, and AD. Although hypoxia-inducible factor-1 alpha (HIF-1α) and signal transducer and activator...

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Bibliographic Details
Main Authors: Mi-Gyeong Gwon, Jaechan Leem, Hyun-Jin An, Hyemin Gu, Seongjae Bae, Jong Hyun Kim, Kwan-Kyu Park
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Oligonucleotides: Therapies and Applications
atopic dermatitis
mast cell
HIF-1α
STAT5
decoy oligodeoxynucleotide
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123002548

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http://www.sciencedirect.com/science/article/pii/S2162253123002548

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