Role of Homologous Fc Fragment in the Potency and Efficacy of Anti‐Botulinum Antibody Preparations

Role of Homologous Fc Fragment in the Potency and Efficacy of Anti‐Botulinum Antibody Preparations

The only approved treatment for botulism relies on passive immunity which is mostly based on antibody preparations collected from hyper‐immune horses. The IgG Fc fragment is commonly removed from these heterologous preparations to reduce the incidence of hyper‐sensitivity reactions. New‐generation t...

Full description

Bibliographic Details
Main Authors: Amram Torgeman, Eyal Ozeri, Alon Ben David, Eran Diamant, Osnat Rosen, Arieh Schwartz, Ada Barnea, Arik Makovitzki, Avishai Mimran, Ran Zichel
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Toxins
Subjects:
botulinum
antitoxin
potency
efficacy
monoclonal antibodies
polyclonal antibodies
Online Access:http://www.mdpi.com/2072-6651/9/6/180

Internet

http://www.mdpi.com/2072-6651/9/6/180

Similar Items