Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease

Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease

Abstract Background Neuroinflammation substantially contributes to the pathology of Alzheimer’s disease (AD), the most common form of dementia. Studies have reported that nuclear factor erythroid 2-related factor 2 (Nrf2) attenuates neuroinflammation in the mouse models of neurodegenerative diseases...

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Bibliographic Details
Main Authors: Ting Wang, Akira Sobue, Seiji Watanabe, Okiru Komine, Takaomi C. Saido, Takashi Saito, Koji Yamanaka
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Neuroinflammation
Subjects:
Alzheimer’s disease
Astrocytes
Neuroinflammation
STAT3
Nrf2
Dimethyl fumarate
Online Access:https://doi.org/10.1186/s12974-024-03046-2

Internet

https://doi.org/10.1186/s12974-024-03046-2

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