Will previous antimicrobial therapy reduce the positivity rate of metagenomic next-generation sequencing in periprosthetic joint infections? A clinical study

Will previous antimicrobial therapy reduce the positivity rate of metagenomic next-generation sequencing in periprosthetic joint infections? A clinical study

BackgroundMetagenomic next-generation sequencing (mNGS) is a culture-independent massively parallel DNA sequencing technology and it has been widely used for rapid etiological diagnosis with significantly high positivity rate. Currently, clinical studies on evaluating the influence of previous antim...

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Bibliographic Details
Main Authors: Linjie Hao, Weiguo Bian, Zhong Qing, Tao Ma, Hui Li, Peng Xu, Pengfei Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
metagenomic next-generation sequencing
antibiotics
periprosthetic joint infection
pathogen detection
positivity rate
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1295962/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1295962/full

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