Extensive breaking of genetic code degeneracy with non-canonical amino acids

Extensive breaking of genetic code degeneracy with non-canonical amino acids

Abstract Genetic code expansion (GCE) offers many exciting opportunities for the creation of synthetic organisms and for drug discovery methods that utilize in vitro translation. One type of GCE, sense codon reassignment (SCR), focuses on breaking the degeneracy of the 61 sense codons which encode f...

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Bibliographic Details
Main Authors: Clinton A. L. McFeely, Bipasana Shakya, Chelsea A. Makovsky, Aidan K. Haney, T. Ashton Cropp, Matthew C. T. Hartman
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40529-x

Internet

https://doi.org/10.1038/s41467-023-40529-x

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