<i>Marrubium alysson</i> L. Ameliorated Methotrexate-Induced Testicular Damage in Mice through Regulation of Apoptosis and miRNA-29a Expression: LC-MS/MS Metabolic Profiling

<i>Marrubium alysson</i> L. Ameliorated Methotrexate-Induced Testicular Damage in Mice through Regulation of Apoptosis and miRNA-29a Expression: LC-MS/MS Metabolic Profiling

Despite the efficient anti-cancer capabilities of methotrexate (MTX), it may induce myelosuppression, liver dysfunction and testicular toxicity. The purpose of this investigation was to determine whether <i>Marrubium alysson</i> L. (<i>M. alysson</i> L.) methanolic extract an...

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Bibliographic Details
Main Authors: Reda F. A. Abdelhameed, Asmaa I. Ali, Sameh S. Elhady, Hend E. Abo Mansour, Eman T. Mehanna, Sarah M. Mosaad, Salma A. Ibrahim, Rawan H. Hareeri, Jihan M. Badr, Nermeen A. Eltahawy
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Plants
Subjects:
sustainability of natural resources
drug discovery
<i>Marrubium alysson</i> L.
metabolomic profiling
methotrexate
testicular damage
Online Access:https://www.mdpi.com/2223-7747/11/17/2309

Internet

https://www.mdpi.com/2223-7747/11/17/2309

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