Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway

Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway

Cocaine administration alters the microRNA (miRNA) landscape in the cortico-accumbal pathway. These changes in miRNA can play a major role in the posttranscriptional regulation of gene expression during withdrawal. This study aimed to investigate the changes in microRNA expression in the cortico-acc...

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Bibliographic Details
Main Authors: Vidhya Kumaresan, Yolpanhchana Lim, Poorva Juneja, Allison E. Tipton, Giordano de Guglielmo, Lieselot L. G. Carrette, Marsida Kallupi, Lisa Maturin, Ying Liu, Olivier George, Huiping Zhang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Biomedicines
Subjects:
protracted abstinence
outbred heterogeneous stock rats
prefrontal cortex
nucleus accumbens
rat brain miRNA
small RNA sequencing
Online Access:https://www.mdpi.com/2227-9059/11/5/1368

Internet

https://www.mdpi.com/2227-9059/11/5/1368

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