Synthesis and analysis of small molecules to restrain the function of tissue factor within tumour cells

Introduction: The restriction of prolyl-protein cis/trans isomerase 1 (Pin1) activity has been shown to prevent the release of tissue factor (TF) leading to the accumulation of the latter protein within the cell. This study tested the ability of novel small molecules to inhibit Pin1, suppress TF act...

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Bibliographic Details
Main Authors: Oluremi I Adeniran, Mohammad A Mohammad, Sophie Featherby, Anthony Maraveyas, Andrew N Boa, Camille Ettelaie
Format: Article
Language:English
Published: IMR Press 2021-10-01
Series:Frontiers in Bioscience-Landmark
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/26/10/10.52586/4985