Genetic and Functional Characterization of Congenital HCMV Clinical Strains in Ex Vivo First Trimester Placental Model

Genetic and Functional Characterization of Congenital HCMV Clinical Strains in Ex Vivo First Trimester Placental Model

Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, leading to a variety of symptoms in the unborn child that range from asymptomatic to death in utero. Our objective was to better understand the mechanisms of placental infection by HCMV clinical strains, particularly du...

Full description

Bibliographic Details
Main Authors: Deborah Andouard, Valentin Tilloy, Elodie Ribot, Melissa Mayeras, Daniel Diaz-Gonzalez, Chahrazed El Hamel, Fabienne Piras-Douce, Nathalie Mantel, Sophie Alain
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pathogens
Subjects:
congenital cytomegalovirus
clinical strains
placenta
viral kinetics
mutations
Online Access:https://www.mdpi.com/2076-0817/12/8/985

Internet

https://www.mdpi.com/2076-0817/12/8/985

Similar Items