Modelling Protein Plasticity: The Example of Frataxin and Its Variants
Frataxin (FXN) is a protein involved in storage and delivery of iron in the mitochondria. Single-point mutations in the <i>FXN</i> gene lead to reduced production of functional frataxin, with the consequent dyshomeostasis of iron. FXN variants are at the basis of neurological impairment...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-03-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/6/1955 |