Urocortin 2 promotes hypertrophy and enhances skeletal muscle function through cAMP and insulin/IGF-1 signaling pathways

Urocortin 2 promotes hypertrophy and enhances skeletal muscle function through cAMP and insulin/IGF-1 signaling pathways

Objective: Although it is well established that urocortin 2 (Ucn2), a peptide member of the corticotrophin releasing factor (CRF) family, and its specific corticotrophin-releasing factor 2 receptor (CRF2R) are highly expressed in skeletal muscle, the role of this peptide in the regulation of skeleta...

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Bibliographic Details
Main Authors: Natalia Lautherbach, Dawit A.P. Gonçalves, Wilian A. Silveira, Sílvia Paula-Gomes, Rafael Rossi Valentim, Neusa M. Zanon, Marcelo G. Pereira, Elen H. Miyabara, Luiz C.C. Navegantes, Isis C. Kettelhut
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Molecular Metabolism
Subjects:
Urocortin 2
Hypertrophy
Fatigue resistance
cAMP
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822000618

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http://www.sciencedirect.com/science/article/pii/S2212877822000618

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