Unraveling the Structure of Meclizine Dihydrochloride with MicroED

Abstract Meclizine (Antivert, Bonine) is a first‐generation H1 antihistamine used in the treatment of motion sickness and vertigo. Despite its wide medical use for over 70 years, its crystal structure and the details of protein‐drug interactions remained unknown. Single‐crystal X‐ray diffraction (SC...

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Bibliographic Details
Main Authors: Jieye Lin, Johan Unge, Tamir Gonen
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202306435