Urinary epidermal growth factor reflects vascular health in boys with either obesity or type 1 diabetes. A role for renin, or beyond?

An increased blood pressure is a known comorbidity of both type 1 diabetes (T1DM) and obesity in children. Increasing evidence suggests a subtle interplay between epidermal growth factor (EGF) and renin along the juxtaglomerular system, regulating the impact of blood pressure on kidney health and th...

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Bibliographic Details
Main Authors: Kristien J. Ledeganck, Annelies Van Eyck, Kristien Wouters, Eline Vermeiren, Benedicte Y. De Winter, Stijn Verhulst, Kim Van Hoorenbeeck, Annick France, Hilde Dotremont, Marieke den Brinker, Dominique Trouet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062545/?tool=EBI