Protective effects of PARP-1 knockout on dyslipidemia-induced autonomic and vascular dysfunction in ApoE mice: effects on eNOS and oxidative stress.

Protective effects of PARP-1 knockout on dyslipidemia-induced autonomic and vascular dysfunction in ApoE mice: effects on eNOS and oxidative stress.

The aims of this study were to investigate the role of poly(ADP-ribose) polymerase (PARP)-1 in dyslipidemia-associated vascular dysfunction as well as autonomic nervous system dysregulation. Apolipoprotein (ApoE)(-/-) mice fed a high-fat diet were used as a model of atherosclerosis. Vascular and aut...

Full description

Bibliographic Details
Main Authors: Chetan P Hans, Yumei Feng, Amarjit S Naura, Mourad Zerfaoui, Bashir M Rezk, Huijing Xia, Alan D Kaye, Khalid Matrougui, Eric Lazartigues, A Hamid Boulares
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2757717?pdf=render

Internet

http://europepmc.org/articles/PMC2757717?pdf=render

Similar Items