Circulating mitochondrial cell-free DNA dynamics in patients with mycobacterial pulmonary infections: Potential for a novel biomarker of disease

Circulating mitochondrial cell-free DNA dynamics in patients with mycobacterial pulmonary infections: Potential for a novel biomarker of disease

ObjectivesHuman mitochondrial cell-free DNA (Mt-cfDNA) may serve as a useful biomarker for infectious processes. We investigated Mt-cfDNA dynamics in patients with pulmonary mycobacterial infections to determine if this novel biomarker could be used to differentiate disease states and severity.Metho...

Full description

Bibliographic Details
Main Authors: Sheng-Wei Pan, Rehan R. Syed, Donald G. Catanzaro, Mei-Lin Ho, Chin-Chung Shu, Tsung-Yeh Tsai, Yen-Han Tseng, Jia-Yih Feng, Yuh-Min Chen, Wei-Juin Su, Antonino Catanzaro, Timothy C. Rodwell
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
cell-free DNA
mitochondria
pulmonary tuberculosis
treatment response monitoring
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1040947/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1040947/full

Similar Items