Novel pyrrolopyrimidine derivatives: design, synthesis, molecular docking, molecular simulations and biological evaluations as antioxidant and anti-inflammatory agents

Novel pyrrolopyrimidine derivatives: design, synthesis, molecular docking, molecular simulations and biological evaluations as antioxidant and anti-inflammatory agents

Current medical approaches to control the Covid-19 pandemic are either to directly target the SARS-CoV-2 via innovate a defined drug and a safe vaccine or indirectly target the medical complications of the virus. One of the indirect strategies for fighting this virus has been mainly dependent on usi...

Full description

Bibliographic Details
Main Authors: Amira I. Sayed, Yara E. Mansour, Mohamed A. Ali, Omnia Aly, Zainab M. Khoder, Ahmed M. Said, Samar S. Fatahala, Rania H. Abd El-Hameed
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Pyrrolopyrimidines
cytotoxicity
macrophages-RAW 267.4
DPPH
molecular docking
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2022.2090546

Internet

https://www.tandfonline.com/doi/10.1080/14756366.2022.2090546

Similar Items