Novel pyrrolopyrimidine derivatives: design, synthesis, molecular docking, molecular simulations and biological evaluations as antioxidant and anti-inflammatory agents

Novel pyrrolopyrimidine derivatives: design, synthesis, molecular docking, molecular simulations and biological evaluations as antioxidant and anti-inflammatory agents

Current medical approaches to control the Covid-19 pandemic are either to directly target the SARS-CoV-2 via innovate a defined drug and a safe vaccine or indirectly target the medical complications of the virus. One of the indirect strategies for fighting this virus has been mainly dependent on usi...

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Bibliographic Details
Main Authors: Amira I. Sayed, Yara E. Mansour, Mohamed A. Ali, Omnia Aly, Zainab M. Khoder, Ahmed M. Said, Samar S. Fatahala, Rania H. Abd El-Hameed
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Pyrrolopyrimidines
cytotoxicity
macrophages-RAW 267.4
DPPH
molecular docking
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2022.2090546

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