Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry

Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry

Concern over per- and polyfluoroalkyl substances (PFAS) has increased as more is learned about their environmental presence, persistence, and bioaccumulative potential. The limited monitoring, toxicokinetic (TK), and toxicologic data available are inadequate to inform risk across this diverse domain...

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Bibliographic Details
Main Authors: Anna Kreutz, Matthew S. Clifton, W. Matthew Henderson, Marci G. Smeltz, Matthew Phillips, John F. Wambaugh, Barbara A. Wetmore
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Toxics
Subjects:
PFAS
toxicokinetics
in vitro–in vivo extrapolation
plasma protein binding
hepatic clearance
new approach methods
Online Access:https://www.mdpi.com/2305-6304/11/5/463

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https://www.mdpi.com/2305-6304/11/5/463

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