Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection

Cerebrospinal fluid (CSF) flowing through periarterial spaces is integral to the brain’s mechanism for clearing metabolic waste products. Experiments that track tracer particles injected into the cisterna magna (CM) of mouse brains have shown evidence of pulsatile CSF flow in perivascular spaces sur...

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Bibliographic Details
Main Authors: Aditya Raghunandan, Antonio Ladron-de-Guevara, Jeffrey Tithof, Humberto Mestre, Ting Du, Maiken Nedergaard, John H Thomas, Douglas H Kelley
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/65958