Rapid and Efficient Synthesis of Succinated Thiol Compounds via Maleic Anhydride Derivatization

Succination is a non-enzymatic post-translational modification of cysteine (Cys) residues, resulting in the formation of <i>S</i>-(2-succino)cysteine (2SC). While hundreds of 2SC-modified proteins have been identified and are associated with the dysfunction of proteins, the underlying mo...

Полное описание

Библиографические подробности
Главные авторы: Hiroshi Yamaguchi, Hikari Sugawa, Himeno Takahashi, Ryoji Nagai
Формат: Статья
Язык:English
Опубликовано: MDPI AG 2025-01-01
Серии:Molecules
Предметы:
Online-ссылка:https://www.mdpi.com/1420-3049/30/3/571