FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway

FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway

Background: Cardiac hypertrophy was accompanied by various cardiovascular diseases (CVDs), and due to the high global incidence and mortality of CVDs, it has become increasingly critical to characterize the pathogenesis of cardiac hypertrophy. We aimed to determine the metabolic roles of fatty acid...

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Bibliographic Details
Main Authors: Lingfang Zhuang, Ye Mao, Zizhu Liu, Chenni Li, Qi Jin, Lin Lu, Rong Tao, Xiaoxiang Yan, Kang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiac hypertrophy
PPARα
HFABP
metabolism
FAO
glycolysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.722908/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.722908/full

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