Pharmacology-based ranking of anti-cancer drugs to guide clinical development of cancer immunotherapy combinations
Abstract The success of antibodies targeting Programmed cell death protein 1 (PD-1) and its ligand L1 (PD-L1) in cancer treatment and the need for improving response rates has led to an increased demand for the development of combination therapies with anti-PD-1/PD-L1 blockers as a backbone. As more...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-10-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13046-021-02111-5 |