The Persistence-Inducing Toxin HokB Forms Dynamic Pores That Cause ATP Leakage

The Persistence-Inducing Toxin HokB Forms Dynamic Pores That Cause ATP Leakage

ABSTRACT Bacterial populations harbor a small fraction of cells that display transient multidrug tolerance. These so-called persister cells are extremely difficult to eradicate and contribute to the recalcitrance of chronic infections. Several signaling pathways leading to persistence have been iden...

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Bibliographic Details
Main Authors: Dorien Wilmaerts, Mariam Bayoumi, Liselot Dewachter, Wouter Knapen, Jacek T. Mika, Johan Hofkens, Peter Dedecker, Giovanni Maglia, Natalie Verstraeten, Jan Michiels
Format: Article
Language:English
Published: American Society for Microbiology 2018-09-01
Series:mBio
Subjects:
persistence
pore-forming peptide
toxin-antitoxin modules
Online Access:https://journals.asm.org/doi/10.1128/mBio.00744-18

Internet

https://journals.asm.org/doi/10.1128/mBio.00744-18

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