Berberine Attenuates Macrophages Infiltration in Intracranial Aneurysms Potentially Through FAK/Grp78/UPR Axis

Berberine Attenuates Macrophages Infiltration in Intracranial Aneurysms Potentially Through FAK/Grp78/UPR Axis

Background: Inflammatory cells, such as macrophages, play key roles in the pathogenesis of intracranial aneurysms (IAs). Berberine (BBR), an active component of a Chinese herb Coptis chinensis French, has been shown to have anti-inflammatory properties through suppressing macrophage migration in var...

Full description

Bibliographic Details
Main Authors: Kai Quan, Sichen Li, Dongdong Wang, Yuan Shi, Zixiao Yang, Jianping Song, Yanlong Tian, Yingjun Liu, Zhiyuan Fan, Wei Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
Berberine
Focal adhesion kinase
endoplasmic reticulum stress
intracranial aneurysm
macrophage
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00565/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00565/full

Similar Items