Paternally expressed Peg3 controls maternally expressed Zim1 as a trans factor.

The expression of two adjacent imprinted genes, Peg3 and Zim1, is inversely correlated: down-regulation of Peg3 coinciding with up-regulation of Zim1. The current study characterized this inverse correlation using a mutant allele targeting Peg3. According to the results, the mutation on the paternal...

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Bibliographic Details
Main Authors: An Ye, Hongzhi He, Joomyeong Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4180786?pdf=render