A convenient synthesis of CHF<sub>2</sub>O-containing pyrrolidines and related compounds — Perspective building blocks for drug discovery
Fluorine-containing organic molecules, including CHF2O-derivatives, are among the most sought-after in medicinal chemistry. In the current work, a mini-library of 21 compounds with a CHF2O-motif incorporated with azetidine, pyrrolidine (proline), piperidine, 2-azabicyclo[2.2.1]heptane, and 8-azabicy...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
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| Series: | SynOpen |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/a-2407-4709 |