Correlation between the number of false positive variants and the quality of results using Ion Torrent PGM™ sequencing to screen BRCA genes

Correlation between the number of false positive variants and the quality of results using Ion Torrent PGM™ sequencing to screen BRCA genes

Introduction: Next Generation Sequencing (NGS) is cost-effective and a faster method to study genes, but its protocol is challenging. Objective: To analyze different adjustments to the protocol for screening the BRCA genes using Ion Torrent PGM sequencing and correlate the results with the number of...

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Bibliographic Details
Main Authors: Tiago César Gouvêa Moreira, Pricila da Silva Spínola, Micheline Campos Rezende, Carla Simone Moreira de Freitas, Fábio Borges Mury, Cibele Rodrigues Bonvicino, Luciana de Andrade Agostinho
Format: Article
Language:English
Published: Instituto Nacional de Salud 2021-12-01
Series:Biomédica: revista del Instituto Nacional de Salud
Subjects:
sequence analysis
dna
high-throughput nucleotide sequencing
genes, brca1
genes, brca2
Online Access:https://revistabiomedica.org/index.php/biomedica/article/view/5663

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https://revistabiomedica.org/index.php/biomedica/article/view/5663

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