Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases

Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases

Ras homolog (Rho)-associated kinases (ROCKs) belong to the serine-threonine kinase family, which plays a pivotal role in regulating the damage, survival, axon guidance, and regeneration of neurons. ROCKs are also involved in the biological effects of immune cells and glial cells, as well as the deve...

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Bibliographic Details
Main Authors: Qing Wang, Li-Juan Song, Zhi-Bin Ding, Zhi Chai, Jie-Zhong Yu, Bao-Guo Xiao, Cun-Gen Ma
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease; cell-based therapy; central nervous system cells; fasudil; immunocytes; multiple sclerosis; parkinson’s disease; pericytes; rho kinase inhibitor; rho-associated kinases
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=12;spage=2623;epage=2631;aulast=Wang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=12;spage=2623;epage=2631;aulast=Wang

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