Coaggregation of FcεRI with FcγRIIB Inhibits Degranulation but Not Induction of Bcl-2 Family Members A1 and Bim in Mast Cells

<p/> <p>The aggregation of high-affinity immunoglobulin E (IgE) receptors (FcεRI) on mast cells is a critical event in the initiation of an allergic reaction. Coengagement of FcεRI with immunoglobulin G (IgG) low-affinity receptor FcγRIIB/CD32 inhibits degranulation and the release of in...

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Bibliographic Details
Main Authors: Ekoff Maria, Möller Christine, Xiang Zou, Nilsson Gunnar
Format: Article
Language:English
Published: BMC 2006-09-01
Series:Allergy, Asthma & Clinical Immunology
Online Access:http://www.aacijournal.com/content/2/3/87