Boosting the therapeutic potential of cell secretome against osteoarthritis: Comparison of cytokine-based priming strategies

Boosting the therapeutic potential of cell secretome against osteoarthritis: Comparison of cytokine-based priming strategies

The secretome, or conditioned medium (CM), from Mesenchymal Stem/stromal Cells (MSCs) has recently emerged as a promising cell-free therapeutic against osteoarthritis (OA), capable of promoting cartilage regeneration and immunoregulation. Priming MSCs with 10 ng/ml tumor necrosis factor α (TNFα) and...

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Bibliographic Details
Main Authors: Chiara Giannasi, Elena Della Morte, Francesca Cadelano, Alice Valenza, Sara Casati, Michele Dei Cas, Stefania Niada, Anna Teresa Brini
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Secretome
Conditioned medium
Cell priming
Osteoarthritis
Inflammation
Immunoregulation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223017687

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http://www.sciencedirect.com/science/article/pii/S0753332223017687

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