The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

Abstract Background Ovarian cancer (OVCA) is the most lethal gynecologic cancer and chemoresistance remains a major hurdle to successful therapy and survival of OVCA patients. Plasma gelsolin (pGSN) is highly expressed in chemoresistant OVCA compared with their chemosensitive counterparts, although...

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Bibliographic Details
Main Authors: Hafiza Bushra Manzoor, Meshach Asare-Werehene, Satyajit Dey Pereira, Kapaettu Satyamoorthy, Benjamin K. Tsang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
Chemoresistance
DNA methylation
Plasma gelsolin (pGSN)
Ten eleven translocation enzyme isoform 1 (TET1)
Online Access:https://doi.org/10.1186/s13048-023-01332-w

Internet

https://doi.org/10.1186/s13048-023-01332-w

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