Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach

Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach

Abstract Background Blood-retinal barrier cells are known to exhibit a massive phenotypic change during experimental autoimmune uveitis (EAU) development. In an attempt to investigate the mechanisms of blood-retinal barrier (BRB) breakdown at a global level, we studied the gene regulation of total r...

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Bibliographic Details
Main Authors: Deborah A. Lipski, Vincent Foucart, Rémi Dewispelaere, Laure E. Caspers, Matthieu Defrance, Catherine Bruyns, François Willermain
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Ophthalmology
Subjects:
Uveitis
Inflammation
Blood-retinal barrier
RNA-Seq
Transcriptome
Endothelial cells
Online Access:http://link.springer.com/article/10.1186/s12886-020-1333-5

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http://link.springer.com/article/10.1186/s12886-020-1333-5

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